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| Second Basemen Single-Season Strikeouts Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Strikeouts | PA | Year | Career Leaderboard |
| 1. | Frank McLaughlin | 76 | 495 | 1884 | |
| 2. | Jack Farrell | 61 | 657 | 1884 | |
| 3. | Tim Manning | 55 | 628 | 1884 | |
| 4. | Bid McPhee | 52 | 610 | 1884 | |
| 5. | Ed Andrews | 49 | 557 | 1884 | |
| 6. | Fred Dunlap | 48 | 630 | 1884 | |
| 7. | Sam Barkley | 31 | 389 | 1884 | |
| 8. | Ed Caskin | 28 | 273 | 1884 | |
| 9. | Buck Ewing | 27 | 639 | 1884 | |
| 10. | Mike Moynahan | 25 | 469 | 1884 | |
| 11. | Bill Smiley | 24 | 135 | 1884 | |
| 12. | Hugh Nicol | 23 | 331 | 1884 | |
| 13. | Joe Ardner | 21 | 106 | 1884 | |
| 14. | Hardy Richardson | 19 | 142 | 1884 | |
| 15. | Elias Peak | 16 | 144 | 1884 | |
| 16. | Sam Trott | 15 | 382 | 1884 | |
| 17. | Bill Harbidge | 14 | 288 | 1884 | |
| 18. | Marr Phillips | 12 | 274 | 1884 | |
| 19. | Joe Quest | 10 | 95 | 1884 | |
| 20. | Charles Fisher | 8 | 153 | 1884 | |
| Dickie Flowers | 8 | 121 | 1884 | ||
| Harry Wheeler | 8 | 114 | 1884 | ||
| Bob Ferguson | 8 | 34 | 1884 | ||
| 24. | Dave Drew | 7 | 97 | 1884 | |
| Charlie Dougherty | 7 | 81 | 1884 | ||
| 26. | Jack Burdock | 6 | 106 | 1884 | |
| 27. | Ross Barnes | 5 | 101 | 1884 | |
| 28. | Cub Stricker | 3 | 92 | 1884 | |
| Joe Gerhardt | 3 | 21 | 1884 | ||
| 30. | Holly Hollingshead | 2 | 75 | 1884 | |
| 31. | George Creamer | 1 | 33 | 1884 |
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